The eye is not only our window to the world. Reversing perspectives, it also serves as a valuable access point to examine the human body inside out. Indeed, a look through the pupil provides insight into a patient’s overall health status!
Looking into the eye, we may observe not only pathologies affecting the eye itself; but we may also be able to draw deductions on the presence of diseases elsewhere in the body, or even to detect systemic diseases.
As an ontogenetic derivative of the neuroectoderm the eye shares many of the brain’s features, and thus its examination allows for drawing inferences on pathologies in the central nervous system. Thus, ophthalmological diagnostic imaging is able to provide a wide range of insights into the course of internal and neurological diseases, often at an earlier time point than when the first cardinal symptoms of the disease occur.
As ophthalmological assessments provide important data on many different disease entities, they possess a wide applicability in clinical research.